LTspice IV runs on PC's running Windows 98, 2000, NT4.0, Me, XP, Vista, or Windows 7. Since a simulation can generate many megabytes of data in a few minutes, free hard disk space (>10GB) and large amount of RAM (>1GB) are recommended. Basically, the program can run on any PC with Windows 98 or above, but the simulation may not finish if there is not enough hard disk space.
There are two bugs in the Windows OS that give some LTspice users trouble. Both bugs relate to Windows hiding the true file name and path of files. Since it is common to use foreign files in LTspice, this can cause confusion.
To circumvent these bugs, please follow the following steps. First, in Windows Explorer, goto to folder options, view, and uncheck "Hide extensions for known file types." Second, on Vista or Windows 7 turn of User Account Control(UAC). UAC can cause the path of files to be different depending on which application is used to view the directory. This breaks the fundamental paradigm of storing files in a computer is it is strongly recommended that you disable UAC. Otherwise it might appear that you have lost files for no apparant reason.
LTspice IV will also run on Linux. The program has been tested on Linux RedHat 8.0 with WINE version 20030219.